Solve these clues to fill the grid.
- A republic in northwestern South America with a coastline on the Pacific Ocean and the Caribbean Sea
- 4 Across
- A route ___ than the usual one
- 7 Across
- Enclosure consisting of a section of canal that can be closed to control the water level (plural)
- 9 Across
- Not practical or realizable
- 11 Across
- A land mass that projects well above its surroundings (plural)
- 13 Across
- An event resulting in great loss and misfortune (plural)
- 14 Across
- Spanish explorer who in 1513 crossed the Isthmus of Darien and became the first European to see
- 15 Across
- A relatively narrow strip of land connecting two larger land areas
- 16 Across
- A republic on the Isthmus of ___
- 1 Down
- A single complete turn
- 2 Down
- Two-winged insect whose female has a long proboscis to pierce the skin and suck the blood of humans
- 3 Down
- A slide of a large mass of dirt and rock down a mountain or cliff (plural)
- 5 Down
- The application of a gas or smoke to something for the purpose of disinfecting it
- 6 Down
- A republic in Central America
- 8 Down
- A rocky headland belonging to Chile at the southernmost tip of South America
- 10 Down
- A location marked by an intense competition and struggle for survival (plural)
- 12 Down